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Specification
Brand : HiMedia Laboratories
BulletPoint1 : Cream to yellow Homogeneous Free flowing powder
BulletPoint2 : Light yellow Clear solution
BulletPoint3 : 5kg weight
ExternallyAssignedProductIdentifier : 08917350709250
ItemName : HiMedia Laboratories MV070-5KG Buffered Glucose HiVeg Broth, 5 kg
ItemPackageDimensions_Height : 11 inches
ItemPackageDimensions_Length : 15 inches
ItemPackageDimensions_Width : 11 inches
ItemPackageQuantity : 1
ItemTypeKeyword : science-lab-natural-proteins
Manufacturer : HiMedia Laboratories, LLC
Material : Glass
ModelNumber : ME443-500G
NumberOfItems : 1
PartNumber : MV070-5KG
ProductDescription : Synonyms: Anti-Dishevelled-1; Anti-Dsh homolog 1; Anti-Segment polarity protein dishevelled homolog Storage: -20C UNSPSC Code: 12352203 Features and Benefits: Antibody BioguaranteeEvaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. General description: The three DVL isoforms display high sequence homology and have conserved DIX, PDZ and DEP domains required for GSK3beta inactivation. DVL1 is highly expressed in adult and fetal tissues such as skeletal muscle and pancreas but is also found in the brain and neural tube. Application: Anti-DVL1 antibody produced in rabbit is suitable for western blot analysis at a working concentration of 1-2++g/mL using HEK-293T cell lysate expressing human DVL1. It was used as a primary antibody at a working dilution of 1:3000 in the immunohistochemical staining of tissue sections of ganglionic and aganglionic colon segments to understand the expression of dishevelled gene in Hirschsprung's disease. Biochem/physiol Actions: Dishevelled (Dsh, DVL) proteins are part of a multigene family that mediate wnt signaling pathways that are essential for the regulation of cellular proliferation, differentiation, motility, and morphogenesis. DVL1 regulates the activity of JNK (c-Jun N-terminal kinase) and GSK3+Ý in the wnt signaling pathway. Upon activation of the wnt signaling pathway, DVL1 inactivates GSK3+Ý through complex formation with APC (Antigen-presenting cell), +Ý-catenin and axin proteins, releasing +Ý-catenin from degradation. In neurons, DVL1 is localized to axonal microtubules and stabilizes microtubules by inhibiting the GSK3+Ý mediated phosphorylation of MAP-1B. Immunogen: synthetic peptide corre
ProductSiteLaunchDate : 2016-12-16T08:00:01.000Z
UnitCount : 1
UnspscCode : 41120000